Answer :
The correct option is D : Prophase is the initial stage of mitosis, which is the process by which the duplicated genetic material carried in the nucleus of a parent cell is separated into two identical daughter cells.
During prophase, the nucleus's combination of DNA and proteins, known as chromatin, condenses.
Colchicine's inhibit the development of spindles during mitotic metaphase. As a result, it hinders chromosomal separation during the anaphase stage. Colchicine is a mitotic inhibitor, which means it suppresses the M phase.
Colchicine, an alkaloid drug derived from the corm of the autumn crocus (Colchicum autumnale), arrests mitosis in metaphase by interfering with the formation of spindle fibrils, thereby slowing centromere division and preventing centriole division.
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Full Question
Colchicine is a drug that is used in plant breeding to create polyploids. It blocks the assembly of microtubules. If dividing cells are treated with colchicine, at what stage of mitosis would you predict the arrest would occur?
A. late anaphase
B. metaphase
C. G1 of interphase
D. prophase
E. telophase