Thiazide diuretics can cause orthostatic changes, so individuals should reposition slowly. Additionally, some patients may notice increased sensitivity to light, so protective measures should be taken.
Thiazide diuretics are an FDA-approved class of drugs that inhibit the reabsorption of 3% to 5% of luminal sodium in the distal convoluted tubule of the nephron. As a result, thiazide diuretics promote natriuresis and diuresis. Examples: chlorothiazide. Chlorthalidone. Indapamide. metolazone. Hydrochlorothiazide.
Side effects of Thiazide diuretics: increase blood uric acid levels. dizziness and drowsiness, blurry vision, decreased appetite, itch, upset stomach, with a headache. weakness.
Hydrochlorothiazide (HCTZ) and chlorthalidone are both thiazide diuretics recommended as first-line treatment for hypertension because of their benefits for heart health and all-cause mortality.
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