Studies show that young people with higher-than-average blood pressure and their families have a history of high blood pressure are more likely than others to develop a severe form of the condition.
(A) and their families have a history of high blood pressure
(B) whose families have a history of high blood pressure
(C) and a history of high blood pressure runs in the family
(D) whose families have a history of high blood pressure running in them
(E) with a history of high blood pressure running in their family

Young people with higher-than-average blood pressure and their families have a history of high blood pressure are more likely than others to develop a severe form of the condition is Whose families have a history of high blood pressure is correct.

Notice that “whose” is a relative pronoun, a noun modifier that is modifying a little far away noun “young people”. This is so because the prepositional phrase preceding “whose” cannot be placed anywhere else in the sentence without affecting the meaning. Hence, the relative pronoun can jump over “with higher-than-average blood pressure” to modify “young people”.The prevalence of high blood pressure among African Americans is the highest in the world. Also called as hypertension, high blood pressure increases your risk of heart disease and stroke, and it can cause permanent damage to the heart before you even notice any symptoms, which is why it is often calls him the "silent killer".

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