The Raynaud phenomenon has a type iii hypersensitivity reaction mechanism in which immune complexes are deposited in tissues after antibodies bind to soluble antigens and are released into bodily fluids.
Immune complexes, which are lattices of antibodies and antigen, are formed when antibodies react to soluble antigen. Immune complexes (IgG or IgM), which are typically cleared by macrophages in the spleen or liver, become too numerous to be handled by these protective mechanisms.
Antigen-antibody aggregates known as "immune complexes," which are mediated by aberrant immunological responses in type III hypersensitivity reactions.
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