Cystic fibrosis is caused by recessive loss-of-function mutations in a locus that encodes a transmembrane conductance regulator. The mutation rate creating new cystic fibrosis alleles is approximately 6. 7×10-7. Assuming that individuals with cystic fibrosis never survive to reproduce, what is the expected frequency of the cystic fibrosis allele at the equilibrium between mutation and selection?.

Cystic fibrosis is caused by recessive loss of function mutations in a locus that encodes a transmembrane conductance regulator. The mutation rate creating new cystic fibrosis alleles is approximately [tex]6.7 X 10^{-7}[/tex]. Since individuals with cystic fibrosis never survive to reproduce the expected frequency of cystic fibrosis allele at the equilibrium between mutation and selection is [tex]\sqrt{6.7X10^{-7} }[/tex] which is 0.0008.

Cystic fibrosis is a condition that damages your lungs, digestive tract, and other organs. It is caused by defective genes that are passed on from generation to generation. Cystic fibrosis mainly impacts the cells that create sweat, digestive juices, and mucus.

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