Answer :
The complication in this excerpt from The Strange Case of Dr. Jekyll and Mr. Hyde is "Dr. jekyll’s formula will work only with an impure salt he can no longer find".
The excerpt from The Strange Case of Dr. Jekyll and Mr. Hyde.
Based on the excerpt, the salt used in Dr Jekyll's experiment which has has never been renewed since he started the experiment has started running low. The new supply ordered for was mixed with draught which made it less efficient.
He has ransacked the whole of London without any positive results, and he has concluded that his first supply of the salt was impure.
Therefore, the answer to the question is "Dr. jekyll’s formula will work only with an impure salt he can no longer find".
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