What is the scale factor from ABC to DEF?

Within similar triangles, the angles are the same. So, we need to look at the side lengths then.
72 to 12
66 to 11
42 to 7
In each pair of corresponding side lengths, the original side length from triangle ABC is divided by 6 (or multiplied by 1/6) to get the smaller side length on triangle DEF.
The scale factor from ABC to DEF is 1/6.
Hope this helps!